Sample Hardy-Weinberg Problems
1. The frequency of two alleles in a gene pool is 0.1 (A) and 0.9 (a).
a. What is the percentage in the population of heterozygous individuals?
b. Of homozygous individuals?
(Assume population is at Hardy-Weinberg equilibrium.)
2. Allele W, for white wool, is dominant over allele w, the black wool. In a sample of 900 sheep, 891 are white and 9 are black.
Estimate the allelic frequencies in this sample, assuming the population is in equilibrium.
3. In a population that is in Hardy-Weinberg equilibrium, the frequency of the recessive homozygote genotype of a certain trait is 0.07.
What is the percentage of individuals homozygous for the dominant allele?
4. Allele T, for the ability to taste a particular chemical, is dominant over allele t, for the inability to taste it. At Cornell University, out of
400 students surveyed, 64 were found to be nontasters. What is the percentage of heterozygous individuals? Assume that the
population is in equilibrium.
5. A rare disease, which is due to a recessive allele that is lethal when homozygous, occurs with a frequency of one in a million. How
many individuals in a town of 14,000 can be expected to carry this allele?
ANSWERS
1. a. 18% Aa, b. 81% aa
2. 0.9 white, 0.1 black
3. 55%
4. 48%
5. about 28 individuals